PATENTS

Intarcia is the assignee on an extensive patent portfolio relating to beneficial agent formulations and osmotic delivery device technology, including device components as well as methods of use and manufacture. This patent estate covers a broad spectrum of beneficial agents, including those for the treatment of endocrine and metabolic disorders. In addition to patents relating to ITCA 650 (exenatide), other Intarcia patents are directed to alternative embodiments.

As of May 28, 2013, Intarcia owns 69 US patents and 14 US applications are pending. Outside of the United States, the portfolio comprises approximately 381 patents and 44 patent applications. Intarcia has filed for patent coverage in major markets throughout the world, including European countries, Japan, China, Korea, Hong Kong, Canada, Mexico, Israel, India, Australia, and New Zealand. The patents have varying years of expiration, and Intarcia continues to file on new inventions.

The following is a list of the 69 issued US patents:

U.S. 5,728,396 U.S. 6,923,800 U.S. 7,919,109
U.S. 5,904,935 U.S. 6,939,556 U.S. 7,959,938
U.S. 5,972,370 U.S. 6,976,981 U.S. 7,964,183
U.S. 5,985,305 U.S. 6,997,922 U.S. 8,048,438
U.S. 5,997,527 U.S. 7,014,636 U.S. 8,052,996
U.S. 6,113,938 U.S. 7,063,681 U.S. 8,080,259
U.S. 6,132,420 U.S. 7,074,423 U.S. 8,114,430
U.S. 6,156,331 U.S. 7,112,335 U.S. 8,114,437
U.S. 6,190,350 U.S. 7,163,688 U.S. 8,158,150
U.S. 6,217,906 U.S. 7,207,982 U.S. 8,173,150
U.S. 6,261,584 U.S. 7,235,068 U.S. 8,206,745
U.S. 6,270,787 U.S. 7,241,457 U.S. 8,211,467
U.S. 6,287,295 U.S. 7,258,869 U.S. 8,257,691
U.S. 6,375,978 U.S. 7,316,680 U.S. 8,268,341
U.S. 6,395,292 U.S. 7,329,242 U.S. 8,273,365
U.S. 6,508,808 U.S. 7,407,499 U.S. 8,298,561
U.S. 6,524,305 U.S. 7,407,500 U.S. 8,298,562
U.S. 6,544,252 U.S. 7,655,254 U.S. 8,299,025
U.S. 6,635,268 U.S. 7,655,257 U.S. 8,343,140
U.S. 6,682,522 U.S. 7,682,356 U.S. 8,367.095
U.S. 6,840,931 U.S. 7,727,519 U.S. 8,372,424
U.S. 6,872,201 U.S. 7,731,947 U.S. 8,398,967
U.S. 6,899,887 U.S. 7,879,028 U.S. 8,440,226